فهرست:
فصل اول : مقدمه
1-1- بیان مسئله.. 2
1-2- کلیات.. 4
1-2-1- دیسانتری.. 4
1-2-1-1- تاریخچه.. 4
1-2-1-2- ابعاد میکروبیولوژی و کلینیکی.. 4
1-2-1-3- اپیدمیولوژی.. 5
1-2-3- شیگلا.. 7
1-2-3-1- اتیولوژی.. 8
1-2-3-2- اپیدمیولوژی.. 8
1-2-3-3- پاتوژنز. 9
1-2-3-4- ایمنی.. 11
1-2-3-5- تظاهرات کلینیکی و عوارض.... 12
1-2-3-6- تشخیص افتراقی.. 15
1-2-3-6- تشخیص..... 15
1-2-3-6- کشت شیگلا.. 16
1-2-3-8- درمان. 17
1-2-3-9- پیشگیری.. 19
1-2-4- سفکسیم.. 20
1-2-5- آزیترومایسین... 20
1-3- اهداف... 21
1-3-1- هدف اصلی.. 21
1-3-2- اهداف ویژه. 21
1-3-3- اهدف کاربردی.. 22
1-4- سؤالات و فرضیات.. 22
1-4-1- سوالات.. 22
1-4-2- فرضیات.. 23
1-5- تعریف واژه‌ها 23
فصل دوم : بررسی متون
2-1- مروری بر مطالعات انجام شده. 25
3-1- نوع مطالعه و جامعه مورد آزمون. 28
3-2- روش نمونه گیری و حجم نمونه.. 28
3-3- روش اجرا 29
3-3-1- معیارهای ورود. 30
3-3-2- معیارهای خروج.. 30
3-4- ابزار جمع آوری اطلاعات و مشخصات آن ها 31
3-5- خطاهای تصادفی و سیستماتیک و روش حل آن ها 31
3-6- نحوه تجزیه و تحلیل اطلاعات.. 31
3-7- جدول متغیرها 32
3-8- ملاحظات اخلاقی.. 33
3-9- محدودیت های اجرایی وروش کاهش آنها 33
فصل چهارم : یافته‌ها
4-1- نتایج... 35
فصل پنجم : بحث و نتیجه گیری
5-1- بحث... 55
5-2- نتیجه گیری.. 58
5-3- پیشنهادات.. 58
منبع:
Reference:
World Health Organization 1988;66(6):709–17. Division of Diarrhoeal and Acute Respiratory Disease Control. The treatment of diarrhoea. A manual for physicians and other senior health workers. Geneva: World Health Organization, 1990:20–1.
Guerrant RL, Hughes JM, Lima NL, Crane J. Diarrhea in developed and developing countries: magnitude, special settings, and etiologies. Reviews of Infectious Diseases 1990;12 Suppl 1: 41–50.
Savarino SJ, Bourgeois AL. EpiDiarrhoeal disease: current concepts and future challenges. Epidemiology of diarrhoeal diseases in developed countries. Transactions of the Royal Society of Tropical Medicine and Hygiene 1993;87 Suppl 3:7–11.
Bern C. The magnitude of the global problem of diarrhoeal disease: a ten-year update. Bulletin of the World Health Organization 1992; 70(6):705–14.
Savarino SJ, Bourgeois AL. EpiDiarrhoeal disease: current concepts and future challenges. Epidemiology of diarrhoeal diseases in developed countries. Transactions of the Royal Society of Tropical Medicine and Hygiene 1993;87 Suppl 3:7–11.
Cunliffe NA, Kilgore PE, Bresee JS, Steele AD, Luo N, Hart CA, et al.Epidemiology of rotavirus diarrhoea in Africa: a review to assess the need for rotavirus immunization. Bulletin of the World Health Organization 1998;76(5):525–37.
Huilan S, Zhen LG, Mathan MM, Mathew MM, Olarte J, Espejo R, et al.Etiology of acute diarrhoea among children in developing countries: a multicentre study in five countries. Bulletin of the World Health Organization 1991;69(5):549–55.
Walker-Smith JA. Diarrhoeal disease: current concepts and future challenges. Malnutrition and infection. Transactions of the Royal Society of Tropical Medicine 1993;87 Suppl 3:13–5.
Salminen S, vonWright A, Morelli L, Marteau P, Brassart D, de Vos WM, et al.Demonstration of safety of probiotics -- a review. International Journal of Food Microbiology 1998;44(1-2):93–106.
Naidu AS, Bidlack WR, Clemens RA. Probiotic spectra of lactic acid bacteria (LAB). Critical Reviews in Food Science and Nutrition 1999;39(1):13–126.
Klein G, Pack A, Bonaparte C, Reuter G. Taxonomy and physiology of the probiotic lactic acid bacteria. International Journal of Food Microbiology 1998;41(2):103–25.
Food and Agriculture Organization of the United Nations (FAO)/World Health Organization (WHO). Joint FAO/WHO expert consultation on evaluation of health and nutritional properties of probiotics in food including powder milk and live lactic acid bacteria. ftp://ftp.fao.es/esn/food/probio_report_en.pdf 2001.
Gismondo MR, Drago L, Lombardi A. Review of probiotics available to modify gastrointestinal flora. International Journal Antimicrobial Agents 1999;12(4):287–92.
Piarroux R, Millon L, Bardonnet K, Vagner O, Koenig H. Are live saccharomyces yeasts harmful to patients?. Lancet 1999;353(9167):1851–2.
Turner D, Ashkenazi S, Mimouni F, Shamir R. Recommendations for the diagnosis and management of pediatric acute gastroenteritis in Israel. Harefuah. 2010 Jan;149(1):53-8, 61, 60.
Vinh HA, et al. A multi center randomized trial to assess the efficacy of Gatifloxacin versus Ciprofloxacin for the treatment of shigellosis in Vietnamese children. Journal of Neglected Tropical Diseases. 2011; 5(8): e1264.
Varsano I, Eidlitz-Marcus T, Nussinovitch M, Elian I. Comparative efficacy of ceftriaxone and ampicillin for treatment of severe shigellosis in children. J Pediatr. 1991;118:627-32.
Salam MA, Bennish ML. Therapy for shigellosis. I. Randomized, double-blind trial of nalidixic acid in childhood shigellosis. J Pediatr. 1988;113:901-7.
Judith M, Pitetti R, Maffei F, Tritt J, Smail K, Ellen R. Treatment of shigellosis with cefixime: two days vs. five days. Pediatric Infectious Disease Journal. 2000; 19(6): 522-26.
Khan WA, Seas C, Dhar U, Salam MA, Bennish ML. Treatment of shigellosis: V. Comparison of azithromycin and ciprofloxacin. A double-blind, randomized, controlled trial. Ann Intern Med. 1997;126(9):697-703.