فهرست:
1-1- بیان مسئله.. 1
1-2- اهداف... 10
1-2-1- هدف اصلی.. 10
1-2-2- اهداف ویژه. 10
1-2-3- اهداف کاربردی.. 12
1-3- سئوالات و فرضیات.. 13
1-4- تعریف واژه‌ها 14
فصل دوم : بررسی متون
2-1- مروری بر مطالعات انجام شده. 16
فصل سوم : مواد و روش کار
3-1- نوع مطالعه.. 20
3-2- روش نمونه گیری.. 20
3-3- جامعه آماری.. 20
3-4- ابزار جمع آوری اطلاعات.. 20
3-5- نحوه تجزیه و تحلیل اطلاعات.. 21
3-6- نحوه محاسبه حجم نمونه و تعداد. 22
3-7- روش اجرا 22
3-8-خطاهای تصادفی و سیستماتیک و روش حل آنها 28
3-9- ملاحظات اخلاقی.. 29
3-10- جدول متغیرها 30
فصل چهارم : یافته‌ها
4-1- نتایج .................................................................................................................................. 32
فصل پنجم : بحث و نتیجه گیری
5-1- بحث و نتیجه‌گیری.. 33
5-2- تحلیل نتایج فرضیات اصلی.. 33
5-3- نتیجه گیری کلی.. 38
5-4- پیشنهادها 38
5-5- منابع.. 40
5-6- پیوست ها
منبع:
1. Sanisbury A, Ford AC.Treatment of irritable bowel syndrome : beyond fiber and antispasmodic agents. Therap Adv Gastroenterol. 2011 Mar ; 4(2) : 115-27.
2. Dorofeyev AE, Kiriyan EA, Vasilenko IV, et al.Clinical endoscopical and morphological efficacy of mesalazine in patients with irritable bowel syndrome. clin Exp Gastroentrol. 2011 ; 4 : 141-53.
3. Yoon SL, Grundmann O, Koepp L, Farrell L. Management of irritable bowel syndrome (IBS) in adults : conventional and complementary/ alternative approaches. Altern Med Rev. 2011 Jun ; 16(2) : 134-51.
4. Enck P. et al. Therapy Options in irritable bowel syndrome. Eurp J Gastroenterol Hepatol. 2010 Dec ; 22 (12) : 1402-11.
5. Kwon JG, et al. Guideline for the treatment of irritable bowel syndrome. Korean J Gastroenterol. 2011 Feb; 057 (02) : 82-99.
6. . Suares NC, Ford AC. Diagnosis and treatment of irritable bowel syndrome. Discov Med. 2011 May ; 11(60) : 425-33.
7. Chey WD, et al. Pharmacologic and complementary and alternative medicine therapies for irritable bowel syndrome. Gut liver. 2011 Sep ; 5(3) : 253-66.
8. Van Citters GW, Lin HC. Management of small intestinal bacterial overgrowth. Curr Gastroenterol Rep. 2005; 7: 317-320. Drouault-Holowacz S, Bieuvelet S,
9. Nobaek S, Johnsson ML, Molin G, Ahrne S, Jeppsson B. Alteration of intestinal microflora is
associated with reduction in abdominal bloating and pain in patients with irritable bowel
syndrome. Am J Gastroenterol. 2000 May; 95(5): 1231-8.
10. 14- O'Mahony L, McCarthy J, Kelly P, Hurley G, Luo F, Chen K, et al. Lactobacillus and
Bifidobacterium in irritable bowel syndrome: symptom responses and relationship to cytokine
profiles. Gastroenterology. 2005 Mar; 128(3): 541-51.
11- Hungin A.P.S et al Systematic review: probiotics in the management of lower gastrointestinal symptoms in clinical practice – an evidencebased international guide Aliment Pharmacol Ther 2013; 38: 864–886
12-Purfarzi F, Enteshari Mogaddam A, Yazdanbod A, Tazakkori Z, Farzaneh E, Mirzarahimi M. The Effect
Probiotic Yogurt on Controlling the Symptoms of Irritable Bowel Syndrome. J Ardabil Univ Med Sci. 2011
11(1): 24-32.
13-Burckel A, Cazaubiel M, Dray X,Marteau P. A double blind randomized controlled trial of a probiotic combination in 100 patients with irritable bowel syndrome. Gastroenterol Clin Biol 2008; 32: 147–52
14-König, Julia, and Robert-Jan Brummer. "Alteration of the intestinal microbiota as a cause of and a potential therapeutic option in irritable bowel syndrome." Beneficial microbes 5.3 (2014): 247-261.
15-de Chambrun, Guillaume Pineton, et al. "A randomized clinical trial of Saccharomyces cerevisiae versus placebo in the irritable bowel syndrome." Digestive and Liver Disease (2014).
16-Lorenzo-Zúñiga, Vicente, et al. "I. 31, a new combination of probiotics, improves irritable bowel syndrome-related quality of life." World journal of gastroenterology: WJG 20.26 (2014): 8709.
17-Søndergaard B, Olsson J, Ohlson K, Svensson U, Bytzer P, Ekesbo R.
Effects of probiotic fermented milk on symptoms and intestinal fl ora in
patients with irritable bowel syndrome: A randomized, placebo-controlled
trial. Scand J Gastroenterol 2011;46:663-72.
18-Amirimani B, Nikfam S, Albaji M, Vahedi S, Nasseri-Moghaddam S, Sharafkhah M, Ansari R, Vahedi H. Probiotic vs. Placebo in Irritable Bowel Syndrome: A Randomized Controlled Trial. Middle East J Dig Dis 2013;5:98-102.
19-Ortiz-Lucas, María, et al. "Effect of probiotic species on irritable bowel syndrome symptoms: A bring up to date meta-analysis." Rev Esp Enferm Dig 105.1 (2013): 19-36.